Historical Survey on Chromatoid Body Research
نویسندگان
چکیده
منابع مشابه
Historical Survey on Chromatoid Body Research
The chromatoid body (CB) is a male reproductive cell-specific organelle that appears in spermatocytes and spermatids. The cytoplasmic granule corresponding to the CB was first discovered some 130 years ago by von Brunn in 1876. Thirty years later the German term "chromatoide Körper" (chromatoid body) was introduced to describe this granule and is still used today. In this review, first, the res...
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The genome of male germ cells is actively transcribed during spermatogenesis to produce phase-specific protein-coding mRNAs and a considerable amount of different noncoding RNAs. Ribonucleoprotein (RNP) granule-mediated RNA regulation provides a powerful means to secure the quality and correct expression of the requisite transcripts. Haploid spermatids are characterized by a unique, unusually l...
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Mutant mice lacking a testis-specific cytoplasmic poly(A) polymerase, PAPOLB/TPAP, exhibit spermiogenesis arrest and male infertility. However, the mechanism by which PAPOLB regulates spermiogenesis remains unclear. In this study, we examined the relationships between PAPOLB and other spermiogenesis regulators present in the chromatoid body (CB). The loss of PAPOLB had no impact either on the a...
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ژورنال
عنوان ژورنال: ACTA HISTOCHEMICA ET CYTOCHEMICA
سال: 2008
ISSN: 0044-5991,1347-5800
DOI: 10.1267/ahc.08010